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The tissue distribution at steady-state for BDP is moderate (20 L) but more extensive for B-17-MP (424 L). Plasma protein binding is moderately high (87%).

Indications

Prophylactic management of mild, moderate or severe asthma

Starting and Maintenance Dose

It is important to gain control of asthma symptoms and optimize pulmonary function as soon as possible. When patients' symptoms remain under satisfactory control, the dose should be titrated to the lowest dose at which effective control of asthma is maintained.

To be effective, inhaled BECLATE Inhaler must be used on a regular basis even when patients are asymptomatic.

Therapy in new patients should be initiated at the following dosages

Mild asthma             : 100 to 200 micrograms per day in two divided doses.

Moderate asthma     : 200 to 400 micrograms per day in two divided doses.

Severe asthma         : 400 to 800 micrograms per day in two divided doses.

Contraindications

BECLATE Inhaler is contraindicated in patients with a history of hypersensitivity to any of its components.